Ayahuasca has traditionally been used in ceremonial contexts in the Amazon basin. In recent decades, however, it has also become the subject of neuroscientific investigation. Researchers have examined how its active compounds — including DMT and beta-carbolines — influence brain activity, connectivity patterns, and cognitive processing. Below is a research-based overview of seven key…
Read more
Scientific research on ayahuasca and depression is still emerging, but several peer-reviewed studies suggest measurable antidepressant effects under controlled conditions. These findings require careful interpretation, especially regarding context, safety, and long-term outcomes. 1. Randomized Controlled Trial in Treatment-Resistant Depression The first double-blind randomized placebo-controlled trial investigating ayahuasca for treatment-resistant depression found significant antidepressant effects compared…
Read more